Kevin McCauley – Addiction and Recovery Update 2020: The Latest Clinical Takeaways from Neuroscience Research

Outline

I. Addiction: a disorder of reward learning, decision-making and self-awareness I. Addiction: a disorder of reward learning, decision-making and self-awareness

• Definitions of Addiction Definitions of Addiction
  • The American Society of Addiction Medicine’s Definition of AddictionThe American Society of Addiction Medicine’s Definition of Addiction
  • The DSM-5 Symptomology of Addiction (Substance Use Disorder)The DSM-5 Symptomology of Addiction (Substance Use Disorder)
• The Five Current, Leading Neuroscientific Explanations of Addiction The Five Current, Leading Neuroscientific Explanations of Addiction
  • Genetic Vulnerability (Blum)Genetic Vulnerability (Blum)
  • Incentive-Sensitization (Robinson and Berridge)Incentive-Sensitization (Robinson and Berridge)
  • Pathology of Memory and Learning (Kalivas)Pathology of Memory and Learning (Kalivas)
  • Stress-induced Allostasis (Koob and LeMoal)Stress-induced Allostasis (Koob and LeMoal)
  • Pathology of Motivation and Choice (Volkow, Goldstein)Pathology of Motivation and Choice (Volkow, Goldstein)
• The Debate about Addiction’s Definition as a DiseaseThe Debate about Addiction’s Definition as a Disease

II. Recent Advances in the Pathophysiology of Addiction II. Recent Advances in the Pathophysiology of Addiction

• Epigenetics: a new understanding of heritability of addiction & recovery Epigenetics: a new understanding of heritability of addiction & recovery
  • The Overkalix Study and transgenerational trauma transmissionThe Overkalix Study and transgenerational trauma transmission
  • Nicotine primes cocaine use (Kandel and Kandel)Nicotine primes cocaine use (Kandel and Kandel)
• Psychoneuroimmunology: the Gut-Brain-Immune Loop Psychoneuroimmunology: the Gut-Brain-Immune Loop
  • Inflammation and Psychiatric DisordersInflammation and Psychiatric Disorders
  • The Role of Microglia in brain disease and repairThe Role of Microglia in brain disease and repair
• Implications for the Disease ArgumentImplications for the Disease Argument

III. Recovery Management: a Safety-based approach to sobriety III. Recovery Management: a Safety-based approach to sobriety

• Altering Health Disparities by Improving the Social Determinants of HealthAltering Health Disparities by Improving the Social Determinants of Health
• Professional Health Programs: What Makes a Good Aftercare Plan Professional Health Programs: What Makes a Good Aftercare Plan
  • Treatment and “Recovery Literacy”Treatment and “Recovery Literacy”
  • Recovery Management Check-Ups Recovery Management Check-Ups
    • Active Linkage to Recovery-Oriented System of Care (ROSC)Active Linkage to Recovery-Oriented System of Care (ROSC)
  • Recovery ResidencesRecovery Residences
  • Peer-based Sobriety Support (Kelly, Kaskutas)Peer-based Sobriety Support (Kelly, Kaskutas)
  • Relapse Safety PlanningRelapse Safety Planning
  • Urine Drug Testing (Monitoring)Urine Drug Testing (Monitoring)
  • Vocational Rehabilitation and The Collegiate Recovery MovementVocational Rehabilitation and The Collegiate Recovery Movement
  • Addiction Medicine SpecialistsAddiction Medicine Specialists
  • How Recovery Management informs Medication-Assisted TreatmentHow Recovery Management informs Medication-Assisted Treatment
  • “Hedonic Rehabilitation”“Hedonic Rehabilitation”